RepSox (E-616452;SJN 2511;ALK5 INHIBITOR II) _ 53016ESRepSox is a potent and selective inhibitor of TGFR 1, inhibiting ATP binding to ALK5 and inhibiting ALK5 autophosphorylation with IC50s of 23 nM and 4 nM, respectively. RepSox inhibits TGF induced cellular PAI 1 luciferase activity with an IC50 of 18 nM. RepSox can replace the function of Sox2 and induce reprogramming of iPS cells by inhibiting the mechanism of TGFR 1. Features Purity98% Standardized production, using factory mass production mode

hFc Tag with the EC50 of 66

monocytes and eosinophils

It binds specifically to PS exposed on the outer membrane of early apoptotic cells

The cut site should be such that the 5' end protrudes or is flush with the end

Ampicillin binds to penicillin-binding proteins (PBPs)

minimizing variation and enhancing sequencing performance

the protein migrates to 70-80 kDa (GARP)&13 kDa&42-50 kDa (Latent TGF Beta) based on SDS-PAGE result

[36] Yuan HF

Neurite Outgrowth-promoting Factor 2

1038/s41419-021-03897-0(IF:8

SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEGT ESEMETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIAAWMA TYLNDHLEPW IQENGGWDTF VELYGNNAAA ESRKGQERFN R

629350(IF:6